1. Preheat the oven to 400°F (200°C). Bring a large saucepan of salted water to a boil over high heat. Add the macaroni and cook according to the package instructions, until barely tender. Drain well.

2. Meanwhile, heat the oil in a saucepan over medium heat. Add the onion, garlic, and red pepper, and cook, stirring occasionally, for about 5 minutes, or until softened but not browned.

3. Add the tomatoes, ham, wine, and oregano and bring to a boil. Simmer for 2–3 minutes to reduce slightly. Remove from the heat. Stir in the macaroni and season with salt and pepper. Spread in a 2 quart (2 liter) baking dish. Mix the bread crumbs, Parmesan, and butter, and sprinkle on top.

4. Place on a baking sheet and bake for 15–20 minutes, or until golden and bubbling. Serve hot.